Preheat the Oven: Start by preheating your oven to 375°F. Prepare two baking sheets by lining them with parchment paper.
Mix the Coating: In a large bowl, combine the flour, paprika, onion powder, garlic powder, and salt. Add the buttermilk to this mixture and stir until you achieve a thick consistency.
Coat the Cauliflower: Dip each cauliflower floret into the batter, ensuring an even coat. Arrange the coated florets on the prepared baking sheets, spaced out to allow air circulation.
Bake: Place the cauliflower in the oven and bake for 20 minutes. Then, flip each piece over and continue baking for another 20 minutes to ensure an even crispiness.
Prepare the Buffalo Sauce: While the cauliflower bakes, mix the buffalo sauce with the melted butter in a separate bowl.
Toss and Serve: Once baked, toss the cauliflower wings in the buffalo sauce mixture until well coated. Serve immediately and enjoy the burst of flavors.